My 11 year old dog has Cushing's disease so she's experiencing a lot of pain and discomfort from muscle degradation, and also symptoms of anxiety from the excess cortisol in her body. Bully Crew's CBD has made her more calm, better able to sleep and lay down without shaking, and has seemed to improve her condition. I love Bully Crew and all that they do, and I will 100% purchase this agian.